Cornea & External Diseases-Vortex Keratopathy / Cornea Verticillata

Bilateral corneal verticillata in a patient who is treated chronically with amiodarone.

Clinical features:
- Symptoms: the corneal changes are rarely of any visual significance.
- Signs:
  - Symmetric, bilateral, whorl-like pattern of powdery, white, yellow or brown corneal epithelial deposits
  - Appears in a vortex fashion in the inferocentral cornea and swirls outwards sparing the limbus
Occurs in Fabry's disease and in patients being treated with a variety of drugs including amiodarone, chloroquine, amodiaquine, meperidine, indomethacin, chlorpromazine and tamoxifen.

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