Vitreous & Retina




















Macular Diseases
Multiple soft, confluent drusen.

  • Considered to be a feature of AMD.
  • Their presence is associated with increased risk of the development of RPE abnormalities, geographic atrophy and choroidal neovascularization.
  • Clinical features:
    • Symptoms: may have decreased vision or metamorphopsia
    • Signs:
      • Defined as greater than 63µm in diameter
      • Vary in size and shape
      • Occasionally seen as confluent structures with indistinct margins
  • Fluorescein angiogram demonstrates:
    • Early hyperfluorescence
    • Either fading of fluorescence or staining of diffuse drusen in the late phase depending on the phospholipid content
    • Pooling of dye within focal detachments of Bruch's membrane

Copyright © 2003 Digital Reference of Ophthalmology. All rights reserved. All material published on this website is the property of Digital Reference of Ophthalmology and cannot be duplicated without permission.
Home Search Home Search