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Cornea & External Diseases



















Posterior Polymorphous Dystrophy

  • A slowly progressive, uncommon, dominantly inherited condition.
  • Clinical features:
    • Usually bilateral but often asymmetric.
    • Variable clinical features include isolated or coalescent posterior corneal vesicular (the most distinctive characteristic), multi-layered Descemet's membrane thickening and band-like configuration with sharp scalloped margin.
    • The peripheral abnormal multi-layered endothelial cells may cause localized iridocorneal adhesion.
    • Symptom: most cases are asymptomatic and do not require treatment.
  • If the condition progresses to corneal decompensation, definitive treatment with penetrating keratoplasty is usually required.

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