Vitreous & Retina



















Infectious / Inflammatory Disorders
Multiple peripheral histo spots (chorioretinal scars) in presumed ocular histoplasmosis syndrome (POHS).

  • Presumed fungal infection disease which is more prevalent in certain parts of the USA such as Ohio, Mississippi and Nebraska.
  • Also seen in Holland where fungal spores are not present in the soil.
  • Clinical features:
    • Symptoms:
      • Mostly asymptomatic
      • Various degree of visual impairment associated with macular involvement
    • Signs:
      • No vitritis
      • Tetrade:
        1. Atrophic choroidal scars that evolve into discrete, focal, punched-out choroidal lesions
        2. Peripheral streaks
        3. Peripapillary atrophy
        4. Choroidal neovascularization which may occur in the macular region and complicated with macular hemorrhagic detachment and fibrovascular membrane formation
  • Treatment should be considered in cases with significant visual disturbances.

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