- Not an uncommon finding in AMD
- Drusenoid PED may be formed by coalesced multiple large, soft drusen.
- Clinical features:
- Symptoms: reduced vision and metamorphopsia
- Signs:
- Typically appears as dome-shaped, round or oval elevation
of the RPE and its underlying basement membrane
- A detachment of the overlying neurosensory retina may be
an evidence of subretinal neovascularization
- Smooth or homogenous RPE overlying the PED
- May be associated with overlying pigment clumping or atrophy
- May remain stable for several years, but eventually flatten
and lead to geographic atrophy of the RPE
- Fluorescein angiogram:
- Gradual and uniform staining of the sub-RPE material
- Multiple areas of intense, late hyperfluorescence and "notching"
of the uniform hyperfluorescent pooling defect are signs of underlying
occult subretinal neovascularization
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