- Typically develops in middle-aged or elderly white patients.
- Clinical features:
- Almost always unilateral
- Uni- or multifocal, flat, indistinct areas of conjunctival
pigmentation
- Commonly involves the inferior or superior fornices
- May remain stable over years, become smaller, undergo color
changes or malignant transformation
- Work up: multiple biopsies are sometimes required to define the
cytological status of the lesions.
- Management:
- Regular follow-up with photographic documentation.
- Local excision with or without extensive cryotherapy should
be performed if the lesion becomes thicker and demonstrates invasive
nodular formation.
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