The Optic Nerve
Morning Glory Anomaly of the Optic Nerve

  • Rare case and usually unilateral.
  • Affects women more than men with a ratio of 2:1.
  • Clinical features:
    • Symptoms: poor vision, amblyopia and strabismus.
    • Signs:
      • Leukokoria in the first months or years of life
      • Funnel-shaped, excavation of the optic disc and peripapillary retina
      • Enlarged disc with indistinct border surrounded by depigmented areas
      • White, elevated, hyperplastic glial tissues occupies the central disc
      • Abnormally narrow, straight vessels radiated from the disc margins
  • Increased risk of non-rhegmatogenous serous retinal detachment.
  • May be associated with basal encephalocele in patients with mid-line facial defect.

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