- Develop from host immune mechanisms to active infections or antigens
within the stromal keratocytes.
- Diseases known to cause interstitial keratitis include: congenital
syphilis, herpes simplex, herpes zoster, Epstein-Barr, tuberculosis
and leprosy.
- Clinical manifestations: superficial stromal scarring, necrotizing
stromal keratitis and disciform keratitis.
- As the inflammation subsides, intracorneal blood vessels will regress
and become nonperfused vascular channels, which are known as "ghost"
vessels. These vessels can be readily visualized using slit lamp biomicroscopy
and can become active if inflammation recurs.
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