Vitreous & Retina




















Macular Diseases
Fundus photograph demonstrates multiple hard drusen.

  • Commonly present in all ages on fundus photograph.
  • The incidence and prevalence of hard drusen is not age related.
  • Their presence alone is not sufficient to diagnose early age related maculopathy.
  • Hard drusen is not associated with increased risk for the development of choroidal neovascularization.
  • Histologically are globular deposits of hyaline material.
  • Clinical features:
    • Symptoms: typically asymptomatic
    • Signs:
      • Small, hard drusen has been defined as being < 64 µm in diameter
      • Discrete, yellow-white deposits that are external to RPE
      • Almost always have distinct and well-defined border
  • Fluorescein angiogram usually demonstrates pin-point window defect.

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