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Cornea & External Diseases




















Crocodile Shagreen

  • Usually seen in the elderly.
  • Maybe seen in association with peripheral band keratopathy or following trauma.
  • Familial type maybe occurs with X-linked megalocornea or in a juvenile form of anterior mosaic crocodile shagreen.
  • Clinical features:
    • Symptoms: usually asymptomatic
    • Signs:
      • Appears as bilateral, polygonal, grayish-white opacities
      • Anterior shagreen are seen in the deep layers of the epithelium or in Bowman's layer, and become more apparent after instillation of fluorescein drop
      • Posterior shagreen are generally seen in the central deep cornea which makes it difficult to differentiate with a central cloudy dystrophy of the cornea
  • No treatment is required.

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