- Benign choroidal developmental tumors that composed
of melanocytes.
- Clinical features:
- Dark gray - brownish pigmented,
flat or minimally elevated lesion with slightly well demarcated
margin, which size is mostly not greater than a disc diameter
- Commonly associated with overlying
Bruch's membrane changes, drusen depositions, RPE clumping or
migration, serous detachment of the sensory retina or the RPE
- Geographic patches of orange
pigment may overlie the nevi, but may also be an early sign of
a malignant transformation of the lesion
- May be surrounded by a yellowish
ring (halo nevus)
- Choroidal neovascularization membrane associated with exudation or hemorrhage may develop.
- Fluorescein angiography:
- Angiographic features will
vary depend on the degree of pigmentation
- Deeply pigmented nevi will
be relatively hypofluorescent, while less pigmented are tend to
be hyperfluorescent
- When the nevi encroaches or
replaces part of the choriocapillaris, the lesions may appear
hypofluorescence
- Thicker nevi with overlying
drusen will be hyperfluorescent
- Deep-setting nevi that spare
choriocapillaris will give relatively normal fluorescent
- A-scan may have some value in diagnosing elevated lesions.
- Management:
- Ophthalmic examination follow-up
with serial fundus photography, ultrasonography or fluorescein
angiography.
- Photocoagulation when choroidal neovascularization
developed.
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