Astrocytic hamartoma demonstrating initial grayish, flat retinal lesion in the right eye and a typical glistening, yellow, mulberry-like lesion in the left eye.

Congenital tumors. May be found as an isolated finding or in patients who have tuberous sclerosis or rarely in those with neurofibromatosis. Clinical features: Symptoms: depends on the extend and localization of the tumors. Signs: Can be seen as optic nerve or retinal glial tumors Initially appear as grayish, flat and translucent lesions May enlarge and show chalky white-cheesy central area surrounded by grayish margin Typical glistening, yellow, mulberry-like lesions which may become large and calcified Management: Observation.

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