- Dominantly inherited, also called Map-Dot-Fingerprint Dystrophy
or Cogan's microcystic epithelial dystrophy.
- The most common anterior dystrophy incidentally seen in the ophthalmology
practice during routine examination.
- Clinical features:
- Symptoms: more commonly asymptomatic.
- Signs:
- Bilateral, map-like patterns, fingerprint lines, fine dots
(microcysts) or comma-shaped opacities
- After the third decade of life, about 10% of
patients present with recurrent
corneal erosions
- A mild decrease in visual acuity
- Management:
- Symptomatic relief by instillation of hypertonic NaCl ointment
at bedtime.
- Mechanical debridement of the involved corneal epithelium and
basement membrane.
- Anterior stromal micropuncture.
- Phototherapeutic keratectomy may be done in severe case, so
that more normally adherent epithelium may replace the dystrophic
epithelial-basement membrane.
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